SPR-Based Fragment Screening Service

Düsseldorf, Germany · XanTec bioanalytics

Capabilities

SPR is a real-time, label-free analysis of biomolecular interactions we have XanTec's surface plasmon resonance (SPR) systems provide the diverse interests of academia and industry with the most cost-effective, sensitive and flexible platforms in today's marketplace. These systems supply a comprehensive characterization of molecular interactions that are important to researchers in numerous scientific disciplines. These interactions include but are not limited to protein-protein, protein-peptide, protein-nucleic acid and protein-small molecule. Each system generates information-rich data to determine such key parameters as association/dissociation rate constants (ka/kd; kinetics), equilibrium (KD; affinity) constants, thermodynamics (ΔH) and concentration of active compounds in complex media. The systems give invaluable insight into the dynamics of protein, peptide and small molecule binding assays that govern chemical and biological processes. They do not require yearly maintenance plans to keep them in peak performance so researchers do not feel the financial sting of high running costs. In addition to biomolecular interaction studies, XanTec SPR sensors can be used to quantify adsorption and desorption processes in non-biological systems or to follow the course of solid phase-based chemical reactions on the chip surface even in organic solvents. Flexibility. Performance. Value. In cooperation with the industry-leading instrument manufacturer Reichert, we offer three SPR instrument versions which push the limits of detection and sensitivity for label-free, real-time biomolecular interaction analysis — all for a much lower cost than the leading competitor. Each system generates information-rich data to determine such key parameters as association/dissociation rate constants (ka/kd; kinetics), equilibrium (KD; affinity) constants, thermodynamics (ΔH) and concentration of active compounds in complex media. The systems give invaluable insight into the dynamics of protein, peptide and small molecule binding assays that govern chemical and biological processes. They do not require yearly maintenance plans to keep them in peak performance so researchers do not feel the financial sting of high running costs. In addition to biomolecular interaction studies, Reichert’s SPR systems can be used to quantify adsorption and desorption processes in non-biological systems or to follow the course of solid phase-based chemical reactions on the chip surface even in organic solvents. Choose our 2, 3 or 4 channel SPR systems for: High-quality, publication-ready data More flexibility (analyze crude samples, interface with other equipment) Lower equipment costs Lower operating costs No service contract required The best performance-to-cost ratio for individual labs A proven SPR leader since 1997

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